Pharmacoepidemiology of anabolic androgenic steroids: a review

  title={Pharmacoepidemiology of anabolic androgenic steroids: a review},
  author={Ingemar Thiblin and Anna Malou Petersson},
  journal={Fundamental \& Clinical Pharmacology},
Non‐prescribed use of anabolic androgenic steroids (AAS) has been associated with a number of physical and psychiatric/behavioural complications, some of which are potentially lethal. Here, we review both observational and experimental studies on human subjects concerned with such side‐effects. The only physical complication of AAS use that receives definitive support from such investigations is unfavourable changes in blood lipid profiles. Support for various psychiatric complications has also… 
Anabolic Steroid Abuse and Dependence in Clinical Practice
  • K. Brower
  • Medicine, Psychology
    The Physician and sportsmedicine
  • 2009
All physicians who treat nonmedical AAS users will benefit from an understanding of these psychological variables, including the potential for AAS to cause dependence, and guidelines are suggested for assessment and treatment.
Anabolic-androgenic steroid dependence: an emerging disorder.
The accumulating human and animal evidence showing that AAS may cause a distinct dependence syndrome is reviewed, and standard diagnostic criteria for substance dependence must be adapted slightly for cumulatively acting drugs such as AAS.
Anabolic–androgenic steroids and liver injury
A representative case of intrahepatic cholestasis is described with the intention to discuss AAS‐related liver toxicity (including the potential therapeutic role of ursodeoxycholic acid) and to comment on several aspects of the clinical scenario the gastroenterologist should be aware of.
Morbidade hospitalar por ingestão de esteroides anabólico-androgênicos (EAA) no Brasil
The results of this study showed that the hospitalization rate was relatively low for AAS intake; women and individuals aged 15-29 years possessed the highest rates in the period studied.
Anabolic-Androgenic Steroids
The level of evidence for treating anabolic-androgenic steroid dependence is currently based on case reports and series as well as expert opinion, and knowledge of the psychiatric, physical, and laboratory findings aids detection.
Acute and chronic adverse reaction of anabolic–androgenic steroids
Anabolic–androgenic steroids (anabolic androgens, AAS) are widely abused to enhance performance in sport but the underlying personality traits of AAS abusers and concomitant alcohol use, may confound this relationship.
Anabolic Androgenic Steroids in the General Population: User Characteristics and Associations with Substance Use
Lifetime use of anabolic androgenic steroids appears to share common characteristics with illicit substance use, and both substance use variables and physical training remained associated with AAS use when controlling for one another.
nabolic steroids and cardiovascular risk : A national opulation-based cohort study
Non-therapeutic exposure to AAS appears to be an independent risk factor for cardiovascular morbidity and premature death in individuals who tested positive for AAS.


Psychiatric and medical effects of anabolic-androgenic steroid use. A controlled study of 160 athletes.
  • H. Pope, D. Katz
  • Medicine, Psychology
    Archives of general psychiatry
  • 1994
Major mood disturbances associated with anabolic-androgenic steroids may represent an important public health problem for athletes using steroids and sometimes for the victims of their irritability and aggression.
Dermatologists and anabolic-androgenic drug abuse.
The use of huge self-administered dosages of anabolic-androgenic steroids by athletes and body builders is widespread in the United States, increasing at a rapid rate among athletes of both sexes and
Androgenic anabolic steroid use in matric pupils. A survey of prevalence of use in the western Cape.
It is clear that a strategy must be adopted to decrease the prevalence of androgenic anabolic steroids (AAS) use in the schoolgoing population, and general knowledge about AAS was poor, particularly among females and non-sports participants.
Anabolic Steroid Withdrawal Depression: A Case Report
The existence of heterogeneity and the centre effects observed in the analysis suggest a need for caution in the conduct of meta-analyses of antidepressant clinical trials and the comparability of results from different clinical trials should be clearly demonstrated prior to the pooling of data from these studies.
Cause and manner of death among users of anabolic androgenic steroids.
The observations indicate an increased risk of violent death from impulsive, aggressive behavior, or depressive symptoms associated with use of anabolic androgenic steroids and that use of AAS may be the gateway of approach to abuse of other psychotropic drugs.
The use of anabolic-androgenic steroids by Canadian students.
  • P. Melia, A. Pipe, L. Greenberg
  • Medicine
    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
  • 1996
The use of anabolic-androgenic steroids is more widespread than may have been assumed and is often accompanied by high-risk needle-sharing, which represents a special challenge for educators, health professionals, and sport authorities.
Prospective echocardiographic assessment of androgenic-anabolic steroids effects on cardiac structure and function in strength athletes.
Echocardiographic evaluation may provide incomplete assessment of the actual cardiac condition in AAS users since it is not sensitive enough to detect alterations at the cellular level, but no conclusions can be drawn of the cardiotoxic effects of long term AAS abuse.
Symptoms and correlates of anabolic-androgenic steroid dependence.
The data support the notion that AASs are addicting, and suggest that dissatisfaction with body size may lead to dependent patterns of use.
Psychiatric effects and psychoactive substance use in anabolic-androgenic steroid users.
In conclusion, AAS use may lead to psychiatric disorders in certain individuals and concurrent use of psychoactive drugs other than AAS does not appear to be common in intensively training weight lifters and bodybuilders.