Pharmacodynamics of a single low dose of long-acting recombinant follicle-stimulating hormone (FSH-carboxy terminal peptide, corifollitropin alfa) in women with World Health Organization group II anovulatory infertility.

@article{Balen2004PharmacodynamicsOA,
  title={Pharmacodynamics of a single low dose of long-acting recombinant follicle-stimulating hormone (FSH-carboxy terminal peptide, corifollitropin alfa) in women with World Health Organization group II anovulatory infertility.},
  author={Adam H. Balen and Annemarie G. M. G. J. Mulders and Bart C. J. M. Fauser and Benedictus C. Schoot and Monique Adeline Renier and Paul Devroey and M J Struijs and Bernadette M. J. L. Mannaerts},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 12},
  pages={6297-304}
}
In a double-blind, placebo-controlled, randomized study, 55 anovulatory subjects received a single s.c. injection of placebo (n = 10) or recombinant long-acting FSH [FSH-carboxy terminal peptide (CTP), ORG 36286, corifollitropin alfa; NV Organon, The Netherlands] in doses of 7.5 (n = 13), 15 (n = 10), 30 (n = 11), or 60 microg (n = 11). The injection was given 2 or 3 d after the onset of a spontaneous or progestagen-induced withdrawal bleed. After drug administration, the induced follicular… CONTINUE READING

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