Pharmacodynamics in the study of drug resistance and establishing in vitro susceptibility breakpoints: ready for prime time.

@article{Dudley2000PharmacodynamicsIT,
  title={Pharmacodynamics in the study of drug resistance and establishing in vitro susceptibility breakpoints: ready for prime time.},
  author={Michael N. Dudley and Paul G. Ambrose},
  journal={Current opinion in microbiology},
  year={2000},
  volume={3 5},
  pages={515-21}
}
Considerable advancements have been made in providing informative, relevant interpretations of the results of antimicrobial susceptibility tests to clinicians, clinical microbiologists, epidemiologists, and researchers. At the same time, the science of pharmacokinetics has flourished, and the importance of drug exposure in vivo on outcome is now recognized by researchers and clinicians alike. More recently, pharmacokinetic and quantitative measures of antimicrobial susceptibility have been… CONTINUE READING

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