Pharmacodynamics and kinetics of etozolin/ozolinone in hypertensive patients with normal and impaired kidney function

@article{Knauf1984PharmacodynamicsAK,
  title={Pharmacodynamics and kinetics of etozolin/ozolinone in hypertensive patients with normal and impaired kidney function},
  author={Heinrich Knauf and R J Liebig and Peter Schollmeyer and Julian Rosenthal and Ernst Ulrich Koelle and Ernst Mutschler},
  journal={European Journal of Clinical Pharmacology},
  year={1984},
  volume={26},
  pages={687-693}
}
The effect on urinary electrolyte excretion, renin release and plasma norepinephrine of single oral doses of 400 mg etozolin (E) and of 40 mg furosemide (F) were studied in hypertensive patients with normal (n=6) and impaired kidney function (n=6). E caused a marked saluresis up to 24 hours, showing its long duration of action. F, however, displayed a brief… CONTINUE READING