Pharmacodynamic disparities in tacrolimus-treated patients developing cytomegalus virus viremia.


BACKGROUND The optimal balance between efficacy and toxicity of tacrolimus (Tac) treatment remains unsolved. The quantification of nuclear factor of activated T cell (NFAT)-regulated gene expression may provide a tool to monitor the individual susceptibility to Tac. METHODS Expression of NFAT-regulated genes (interleukin-2, interferon-gamma, and… (More)
DOI: 10.1097/FTD.0b013e318226dac7