Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains.

Abstract

Ceftobiprole (BPR) is an investigational cephalosporin with activity against Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA) strains. The pharmacodynamic (PD) profile of BPR against S. aureus strains with a variety of susceptibility phenotypes in an immunocompromised murine pneumonia model was characterized. The BPR MICs of the test… (More)
DOI: 10.1128/AAC.01422-07

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@article{Laohavaleeson2008PharmacodynamicCO, title={Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains.}, author={Somvadee Laohavaleeson and Pamela R Tessier and David Paul Nicolau}, journal={Antimicrobial agents and chemotherapy}, year={2008}, volume={52 7}, pages={2389-94} }