Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies.

@article{Canazza2017PharmacotoxicologicalEO,
  title={Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies.},
  author={Isabella Canazza and Andrea Ossato and Fabrizio Vincenzi and Adolfo Gregori and Fabiana Di Rosa and Federica Nigro and Alessandro Rimessi and Philippe Pinton and Katia Varani and Pier Andrea Borea and Matteo Marti},
  journal={Human psychopharmacology},
  year={2017},
  volume={32 3}
}
INTRODUCTION 5F-ADBINACA, AB-FUBINACA, and STS-135 are 3 novel third-generation fluorinate synthetic cannabinoids that are illegally marketed as incense, herbal preparations, or research chemicals for their psychoactive cannabis-like effects. METHODS The present study aims at investigating the in vitro and in vivo pharmacological activity of 5F-ADBINACA, AB-FUBINACA, and STS-135 in male CD-1 mice, comparing their in vivo effects with those caused by the administration of Δ9 -THC and JWH-018… CONTINUE READING

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