Pharmaco- and toxicokinetics of selected exogenous and endogenous estrogens: A review of the data and identification of knowledge gaps

  title={Pharmaco- and toxicokinetics of selected exogenous and endogenous estrogens: A review of the data and identification of knowledge gaps},
  author={D. Mattison and N. Karyakina and M. Goodman and J. LaKind},
  journal={Critical Reviews in Toxicology},
  pages={696 - 724}
  • D. Mattison, N. Karyakina, +1 author J. LaKind
  • Published 2014
  • Chemistry, Medicine
  • Critical Reviews in Toxicology
  • Abstract Chemicals with estrogenic activity are derived from many different natural and synthetic processes and products, including endogenous production (e.g., estradiol, conjugated estrogens), drugs (e.g., ethinyl estradiol, conjugated estrogens), plants used as foods (phytoestrogens such as genistein, daidzein, S-equol), and man-made chemicals (xenoestrogens such as bisphenol A). Human exposure to low doses of endogenous estrogens, estrogenic drugs, phytoestrogens, and xenoestrogens has the… CONTINUE READING
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