Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.

@article{Miller2015PharmaceuticalsIT,
  title={Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.},
  author={Thomas H. Miller and Gillian L. McEneff and Rebecca Brown and Stewart F. Owen and Nicolas R. Bury and Leon Patrick Barron},
  journal={The Science of the total environment},
  year={2015},
  volume={511},
  pages={153-60}
}
The development, characterisation and application of a new analytical method for multi-residue PPCP determination in the freshwater amphipod, Gammarus pulex are presented. Analysis was performed using pulverised liquid extraction (PuLE), solid phase extraction (SPE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Qualitative method performance offered excellent limits of detection at <20 ng g(-1) for 18 out of 29 compounds. For quantitative application, linearity and precision… CONTINUE READING
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