Pharmaceutical salt of tetrahydroberberine with sulfamic acid prepared via CAHBs

@article{Zhang2020PharmaceuticalSO,
  title={Pharmaceutical salt of tetrahydroberberine with sulfamic acid prepared via CAHBs},
  author={Yu-nan Zhang and Yan-fei Zhang and Lixin Liu and Da-jun Zhang and Zhe Wang and Yu Zhang and Yan-ru Feng and Li-Li Wu and Lei Zhang and Ying-li Liu and Yun-jie Zhang and Dong-yu Zou and Liang Chang and Xin Su and Guangsheng Cheng and Xue-song Zhang},
  journal={Journal of Molecular Structure},
  year={2020},
  volume={1221},
  pages={128816}
}
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4 Citations

4 Citations

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With the aim to improve the solubility and dissolution rate of tetrahydroberberine (THB) by forming hydrochloride salts, three salts of THB, [HTHB]Cl (1), [HTHB]Cl·CH3OH (2) and [HTHB]Cl·CH3COOH (3),…
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Assembly of three pharmaceutical salts/cocrystals of tetrahydroberberine with sulfophenyl acids: improving the properties by formation of charge-assisted hydrogen bonds
The self-recognition of CAHBs could stabilize crystal packing of pharmaceutical salts/cocrystals of THB and improve physicochemical properties of THB.
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