Pharmaceutical co-crystals.

  title={Pharmaceutical co-crystals.},
  author={Peddy Vishweshwar and Jennifer A. McMahon and Joanna A Bis and Michael J Zaworotko},
  journal={Journal of pharmaceutical sciences},
  volume={95 3},
Crystal engineering has evolved in such a manner that it is now synonymous with the paradigm of supramolecular synthesis, that is, it invokes self-assembly of existing molecules to generate a wide range of new solid forms without the need to break or form covalent bonds. This review addresses how crystal engineering has been applied to active pharmaceutical ingredients, API's, with emphasis upon how pharmaceutical co-crystals, a long known but little explored alternative to the four… CONTINUE READING
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