• Corpus ID: 6831188

Pharmaceutical Excipients: A review

@inproceedings{Chaudhari2012PharmaceuticalEA,
  title={Pharmaceutical Excipients: A review},
  author={Shilpa Praveen Chaudhari and Pradeep S Patil},
  year={2012}
}
Excipients play an important role in formulating a dosage form. These are the ingredients which along with Active Pharmaceutical Ingredients make up the dosage forms. Excipients act as protective agents, bulking agents and can also be used to improve bioavailability of drugs in some instances, the following review discusses the various types and sources of excipients along with their uses, and these can be used for different activities. Specific excipients are best suited for a particular… 
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Methods Citations
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ROLE OF EXCIPIENT IN NANO-SUSPENSION
TLDR
The different types and sources of excipients along with their uses, role and these can be used for different activities are discussed.
A review: Pharmaceutical excipients of solid dosage forms and characterizations
TLDR
The most commonly used methods for analysis of solid excipients are flow properties, compressibility index, Hausner index ratios, and angle of repose, while the instrumentation commonly used is Fourier transform infrared spectroscopy, H and C-Nucleo magnetic resonance, Scanning electron microscopy (SEM), Particle size analysis (PSA), X-ray diffraction (XRDP) and Differential scanning calorimeter (DSC).
Current Developments in Excipient Science
Excipient Stability in Oral Solid Dosage Forms: A Review
TLDR
The information available on the physical and chemical instabilities of excipients and their incompatibilities with the active pharmaceutical ingredient in solid oral dosage forms, during various drug-manufacturing processes is reviewed.
Regulatory Aspects of Pharmaceutical Excipients in India and their Qualification to Use in Pharmaceuticals
TLDR
The challenges, regulatory aspects ofexcipients and role of International Pharmaceutical Excipients Council (IPEC) in regulating the quality of excipients are dealt with.
Excipients in parenteral formulations: selection considerations and effective utilization with small molecules and biologics
TLDR
This review article provides an overview of the excipients used exclusively in small molecule and biological parenteral products including solutions, suspensions, and lyophilized formulations, information on the possible drug-excipient and drug-packaging interactions and the regulatory requirements for the use of pharmaceuticalexcipients.
A REVIEW-TYPES OF NATURAL EXCIPIENTS
TLDR
Natural excipients are used in pharmaceutical formulation as binders, diluents, lubricants, glidants, Disintegrants, coatings agents, coloring, flavorings, sweetners and preservatives etc.
An Overview of Pharmaceutical Excipients: Safe or Not Safe?
REVIEW ON NOVEL PHARMACEUTICAL COPROCESSED EXCIPIENTS
Excipients play an important role in formulating a dosage form. In recent years drug formulation scientists have recognized that single component excipients do not always provide the requisite…
Drug-Excipient compatibility studies: First step for dosage form development
TLDR
It is concluded that consequent use of thermal and non-thermal method provide data for drug- excipient interaction which can further help in selection of excipient for the development of stable dosage form.
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References

SHOWING 1-10 OF 22 REFERENCES
Excipients: Background/Introduction
Almost all therapeutic products, including therapeutic products for human and veterinary use, include excipients—indeed, the total amount of excipients frequently used is greater than the amount of…
Applications of novel excipients in the allopathic and herbal formulations
Excipients are additives used to convert active pha rmaceutical ingredients into dosage forms suitable for administration to patients. New and mo dified excipients continue to emerge with better drug…
From functional excipients towards drug carrier systems
The paper describes the state of the art and actual trends in the area of pharmaceutical functional excipients, taking into account the impact of FDA's PAT (Process Analytical Technology) initiative.…
The safety of pharmaceutical excipients.
TLDR
The safety issues regarding excipients can be classified into three categories: quality, toxicology and improper use.
Excipient selection can significantly affect solid-state phase transformation in formulation during wet granulation
TLDR
Investigation of whether excipients with different water sorption behavior affect hydrate formation of nitrofurantoin in wet masses found correct selection of excipient for the formulation can control processing-induced phase transitions and improve the storage stability of the final dosage form.
Maillard reaction of lactose and fluoxetine hydrochloride, a secondary amine.
TLDR
The main conclusion is that drugs which are secondary amines (not just primary amines as sometimes reported) undergo the Maillard reaction with lactose under pharmaceutically relevant conditions.
Container effects on the physicochemical properties of parenteral lipid emulsions.
Migration of antioxidant additives from various polyolefinic plastics into oleaginous vehicles.
Excipients for Pharmaceutical Dosage Forms
Excipients for Semisolid Formulations
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