PharmGKB summary: very important pharmacogene information for RYR1.

Abstract

CYP1A2 is part of the cytochrome P450 (CYP) family of drug-metabolizing enzymes. The CYP1A2 gene is found in a cluster with CYP1A1 and CYP1B1 on chromosome 15 [1]. CYP1A2 and CYP1A1 share a 5′-flanking region of approximately 23 kb, which contains shared regulatory elements, although the genes are positioned back to back and transcription occurs in opposite… (More)
DOI: 10.1097/FPC.0000000000000198

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