Phantom limb pain: a case of maladaptive CNS plasticity?

@article{Flor2006PhantomLP,
  title={Phantom limb pain: a case of maladaptive CNS plasticity?},
  author={Herta Flor and Lone Nikolajsen and Troels Staehelin Jensen},
  journal={Nature Reviews Neuroscience},
  year={2006},
  volume={7},
  pages={873-881}
}
Phantom pain refers to pain in a body part that has been amputated or deafferented. It has often been viewed as a type of mental disorder or has been assumed to stem from pathological alterations in the region of the amputation stump. In the past decade, evidence has accumulated that phantom pain might be a phenomenon of the CNS that is related to plastic changes at several levels of the neuraxis and especially the cortex. Here, we discuss the evidence for putative pathophysiological mechanisms… 

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