Phalloidin attenuates postischemic neutrophil infiltration and increased microvascular permeability.

@article{Korthuis1991PhalloidinAP,
  title={Phalloidin attenuates postischemic neutrophil infiltration and increased microvascular permeability.},
  author={Ronald J. Korthuis and Donna L. Carden and Peter R. Kvietys and David Shepro and John Fuseler},
  journal={Journal of applied physiology},
  year={1991},
  volume={71 4},
  pages={1261-9}
}
The aim of this study was to determine whether phalloidin (1 microM) or antamanide (1 microM), cyclic peptides that stabilize dense peripheral band and stress fiber F-actin in endothelium, would attenuate the increase in microvascular permeability induced by 4 h of ischemia and 30 min of reperfusion (I/R) in the isolated canine gracilis muscle. Changes in microvascular permeability (1 - sigma) were assessed by determining the solvent drag reflection coefficient for total plasma proteins (sigma… CONTINUE READING

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