Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages

Abstract

Several approaches have been used to study the determinants of phagosome-lysosome fusion in intact mouse macrophages. Lysosomes were labeled with the fluorescent vital dye acridine orange and the rate and extent of their fusion with yeast-containing phagosomes was monitored by fluorescence microscopy. Fusion was also assayed by electron microscopy, using… (More)

Topics

8 Figures and Tables

Slides referencing similar topics