Phagocytosis of nucleated and mature beta thalassaemic red blood cells by mouse macrophages in vitro.

@article{Knyszynski1979PhagocytosisON,
  title={Phagocytosis of nucleated and mature beta thalassaemic red blood cells by mouse macrophages in vitro.},
  author={Ahuva Knyszynski and David Danon and Itkhak Kahane and Eliezer A. Rachmilewitz},
  journal={British journal of haematology},
  year={1979},
  volume={43 2},
  pages={251-5}
}
Physiological or experimental decrease in sialic acid (SA) content on the red blood cell (RBC) membrane is believed to play an important role in the recognition of these cells by macrophages. Since there is a 20-30% decrease in the SA content on the membrane of thalassaemic RBC, the interaction between macrophages and these RBC was studied in vitro. Using… CONTINUE READING