Phagocytosis of apoptotic cells and the resolution of inflammation.

  title={Phagocytosis of apoptotic cells and the resolution of inflammation.},
  author={Paola Maderna and Catherine Godson},
  journal={Biochimica et biophysica acta},
  volume={1639 3},
Clearance of apoptotic cells by phagocytic cells plays a significant role in the resolution of inflammation, protecting tissue from harmful exposure to the inflammatory and immunogenic contents of dying cells. Apoptosis induces cell surface changes that are important for recognition and engulfment of cells by phagocytes. These changes include alterations in surface sugars, externalization of phosphatidylserine and qualitative changes in the adhesion molecule ICAM-3. Several studies have… CONTINUE READING