Phagocytosis of Candida albicans induces apoptosis of human neutrophils.

  title={Phagocytosis of Candida albicans induces apoptosis of human neutrophils.},
  author={David Rotstein and Jean C Parodo and Rashmi Taneja and John C. Marshall},
  volume={14 3},
Neutrophil-mediated inflammation is terminated through the programmed cell death or apoptosis of the neutrophil, a process that can be inhibited by soluble mediators released during an inflammatory response. It has been reported, however, that the phagocytosis of intact bacteria can accelerate apoptosis. We evaluated the effects of the phagocytosis of a common nosocomial pathogen, Candida albicans, on the expression of apoptosis. Phagocytosis of killed Candida induced a dose-dependent increase… CONTINUE READING


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