Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.

@article{IbrahimGranet2003PhagocytosisAI,
  title={Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.},
  author={Ouma{\"i}ma Ibrahim-Granet and Bruno Philippe and Haralabia Boleti and Emmanuelle Boisvieux-Ulrich and Dominique Grenet and Maria Stern and Jean Paul Latg{\'e}},
  journal={Infection and immunity},
  year={2003},
  volume={71 2},
  pages={891-903}
}
Aspergillus fumigatus is the most prevalent airborne fungal pathogen responsible for fatal invasive aspergillosis in immunocompromised patients. Upon arrival in the lung alveolus, conidia of A. fumigatus are phagocytosed by alveolar macrophages, the major phagocytic cells of the lung. Engulfment and intracellular trafficking of A. fumigatus conidia in alveolar macrophages of two different origins, the murine cell line MH-S and human pulmonary alveolar macrophages, were analyzed by electron… CONTINUE READING
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