Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling

@article{Everts1996PhagocytosisAI,
  title={Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling},
  author={Vincent E Everts and Erwin van der Zee and Laura B. Creemers and Wouter Beertsen},
  journal={The Histochemical Journal},
  year={1996},
  volume={28},
  pages={229-245}
}
Collagens of most connective tissues are subject to continuous remodelling and turnover, a phenomenon which occurs under both physiological and pathological conditions. Degradation of these proteins involves participation of a variety of proteolytic enzymes including members of the following proteinase classes: matrix metalloproteinases (e.g. collagenase, gelatinase and stromelysin), cysteine proteinases (e.g. cathepsin B and L) and serine proteinases (e.g. plasmin and plasminogen activator… CONTINUE READING
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