Phage influence on the synthesis of extracellular toxins in group A streptococci.

@article{Nida1982PhageIO,
  title={Phage influence on the synthesis of extracellular toxins in group A streptococci.},
  author={S K Nida and Joseph J. Ferretti},
  journal={Infection and immunity},
  year={1982},
  volume={36 2},
  pages={745-50}
}
Phage conversion of group A streptococci to produce streptococcal exotoxins was shown to occur more widely than has been previously reported. Toxigenic conversion was found in 19 newly constructed lysogenic and pseudolysogenic strains resulting in synthesis of exotoxin types A and B. Conversion was accomplished by a positive conversion effector, which was a phage characteristic expressed by the prophage and vegetatively reproducing phage. Exotoxin production was determined by the rabbit skin… CONTINUE READING

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