Phage display of intact domains at high copy number: a system based on SOC, the small outer capsid protein of bacteriophage T4.

@article{Ren1996PhageDO,
  title={Phage display of intact domains at high copy number: a system based on SOC, the small outer capsid protein of bacteriophage T4.},
  author={Z. Justin Ren and George K. Lewis and Paul T Wingfield and Emily G Locke and Alasdair C. Steven and Lindsay W. Black},
  journal={Protein science : a publication of the Protein Society},
  year={1996},
  volume={5 9},
  pages={1833-43}
}
Peptides fused to the coat proteins of filamentous phages have found widespread applications in antigen display, the construction of antibody libraries, and biopanning. However, such systems are limited in terms of the size and number of the peptides that may be incorporated without compromising the fusion proteins' capacity to self-assemble. We describe here a system in which the molecules to be displayed are bound to pre-assembled polymers. The polymers are T4 capsids and polyheads (tubular… CONTINUE READING

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