Phage display in the study of infectious diseases.

  title={Phage display in the study of infectious diseases.},
  author={Lisa M. Mullen and Sean P. Nair and John M Ward and Andrew N. Rycroft and Brian Henderson},
  journal={Trends in microbiology},
  volume={14 3},
Microbial infections are dependent on the panoply of interactions between pathogen and host and identifying the molecular basis of such interactions is necessary to understand and control infection. Phage display is a simple functional genomic methodology for screening and identifying protein-ligand interactions and is widely used in epitope mapping, antibody engineering and screening for receptor agonists or antagonists. Phage display is also used widely in various forms, including the use of… CONTINUE READING