• DOI:10.1073/pnas.1102164108
Corpus ID: 10255224

Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism.

@article{Thompson2011PhageAM,
  title={Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism.},
  author={L. Thompson and Qinglu Zeng and L. Kelly and K. Huang and A. Singer and J. Stubbe and S. Chisholm},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 39},
  pages={
          E757-64
        }
}

L. Thompson, Qinglu Zeng, +4 authors S. Chisholm

Published 2011

Biology, Medicine

Proceedings of the National Academy of Sciences of the United States of America

Cyanophages infecting the marine cyanobacteria Prochlorococcus and Synechococcus encode and express genes for the photosynthetic light reactions. Sequenced cyanophage genomes lack Calvin cycle genes, however, suggesting that photosynthetic energy harvested via phage proteins is not used for carbon fixation. We report here that cyanophages carry and express a Calvin cycle inhibitor, CP12, whose host homologue directs carbon flux from the Calvin cycle to the pentose phosphate pathway (PPP). Phage… CONTINUE READING

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