Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development.

  title={Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development.},
  author={Obinna C. Ubah and C. Barelle and Magdalena J Buschhaus and A. Porter},
  journal={Current pharmaceutical design},
  volume={22 43},
  • Obinna C. Ubah, C. Barelle, +1 author A. Porter
  • Published 2016
  • Biology, Medicine
  • Current pharmaceutical design
  • Phage display technology has revolutionized the science of drug discovery by transforming the generation and manipulation of ligands, such as antibody fragments, enzymes, and peptides. The basis of this technology is the expression of recombinant proteins or peptides fused to a phage coat protein, and subsequent isolation of ligands based on a variety of catalytic, physicochemical/binding kinetic and/or biological characteristics. An incredible number of diagnostic and therapeutic domains have… CONTINUE READING
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