Phage ϕ29 protein p1 promotes replication by associating with the FtsZ ring of the divisome in Bacillus subtilis

@article{BallesterosPlaza2013PhageP,
  title={Phage ϕ29 protein p1 promotes replication by associating with the FtsZ ring of the divisome in Bacillus subtilis},
  author={David Ballesteros-Plaza and Isabel Holguera and D. Scheffers and M. Salas and D. Mu{\~n}oz-Esp{\'i}n},
  journal={Proceedings of the National Academy of Sciences},
  year={2013},
  volume={110},
  pages={12313 - 12318}
}
  • David Ballesteros-Plaza, Isabel Holguera, +2 authors D. Muñoz-Espín
  • Published 2013
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • During evolution, viruses have optimized the interaction with host factors to increase the efficiency of fundamental processes such as DNA replication. Bacteriophage ϕ29 protein p1 is a membrane-associated protein that forms large protofilament sheets that resemble eukaryotic tubulin and bacterial filamenting temperature-sensitive mutant Z protein (FtsZ) polymers. In the absence of protein p1, phage ϕ29 DNA replication is impaired. Here we show that a functional fusion of protein p1 to YFP… CONTINUE READING
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    References

    SHOWING 1-10 OF 50 REFERENCES
    In Vivo Assembly of Phage ϕ29 Replication Protein p1 into Membrane-associated Multimeric Structures*
    • 12
    • PDF
    Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid
    • 34
    • PDF
    Role of penicillin‐binding protein PBP 2B in assembly and functioning of the division machinery of Bacillus subtilis
    • 136
    • Highly Influential
    Polymerization of bacteriophage ø29 replication protein p1 into protofilament sheets
    • 28
    • PDF
    Crystal structure of the bacterial cell-division protein FtsZ
    • 805
    The actin-like MreB cytoskeleton organizes viral DNA replication in bacteria
    • 49
    • PDF