Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults.

@article{Jain2017PhlikeAL,
  title={Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults.},
  author={Nitin Jain and Kathryn G. Roberts and Elias J Jabbour and Keyur Pravinchandra Patel and Agda Karina Eterovic and Ken Chung Chen and Patrick A. Zweidler-McKay and Xinyan Y Lu and Gloria Fawcett and S Alex Wang and Sergej N Konoplev and Richard C Harvey and I-Ming Chen and Debbie Payne-Turner and Marcus B. Valentine and Deborah A. Thomas and Guillermo Garcia-Manero and Farhad Ravandi and Jorge E. Cortes and Steven M. Kornblau and Susan O'brien and Sherry A. Pierce and Jeffrey L. Jorgensen and Kenna R. Mills Shaw and Cheryl L. Willman and Charles G Mullighan and Hagop M Kantarjian and Marina Y Konopleva},
  journal={Blood},
  year={2017},
  volume={129 5},
  pages={572-581}
}
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph-like ALL in adults. Patients with newly diagnosed B-cell ALL (B-ALL) who received frontline chemotherapy at MD Anderson Cancer Center underwent gene expression profiling of leukemic cells. Of 148 patients, 33.1% had Ph-like, 31.1% had Ph+, and 35.8% had other B-ALL subtypes (B-other). Within the Ph-like ALL cohort, 61… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 37 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Atlas of Bone Marrow Pathology

Atlas of Anatomic Pathology • 2018
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Ph-like acute lymphoblastic leukemia in older adults.

The New England journal of medicine • 2014
View 5 Excerpts
Highly Influenced

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…