Peyote and mescaline exposures: a 12-year review of a statewide poison center database

  title={Peyote and mescaline exposures: a 12-year review of a statewide poison center database},
  author={S. Carstairs and F. Cantrell},
  journal={Clinical Toxicology},
  pages={350 - 353}
Background. Peyote, a cactus containing the hallucinogen mescaline, has been used by Native Americans for thousands of years. Illicit use is also known to occur, but reports in the medical literature consist only of isolated case reports. Objectives. We sought to identify characteristics of patients with reported exposure to peyote or mescaline. Methods. We performed a retrospective review of the California Poison Control System database for the years 1997–2008 for all cases of single-substance… Expand
Pharmacokinetic And Pharmacodynamic Aspects Of Peyote And Mescaline: Clinical And Forensic Repercussions.
It is clear that most intoxications appear to be mild and are unlikely to produce life-threatening symptoms, which favors the contemporary interest in the therapeutic potential of the drugs of the class. Expand
Natural psychoactive substance-related exposures reported to United States poison control centers, 2000–2017
While rates of exposure to most natural psychoactive substances decreased during the 18-year study period, rates for marijuana, nutmeg, and kratom increased significantly. Expand
[Emergent drugs (III): hallucinogenic plants and mushrooms].
An increase in the consumption of vegetable substances with a hallucinogenic effect has been observed. Some of these substances are associated with ancestral religious ceremonies, while many of themExpand
Prevalence of reported peyote use 1985-2010 effects of the American Indian Religious Freedom Act of 1994.
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It is hypothesized that social desirability biases suppressed the Pre-AIRFA use rates due to peyote illegal status, and this research adds to the body of evidence regarding the levels of under-reporting of illicit drugs. Expand
When good times go bad: managing ‘legal high’ complications in the emergency department
This review will attempt to group legal agents into expected toxidromes and discuss associated common clinical manifestations and management of patients in the emergency department who have used "legal high” substances. Expand
Guidance on the clinical management of acute and chronic harms of club drugs and novel psychoactive substances.
National guidelines produced by the National Institute for Health and Care Excellence determine the wider principles within which treatment and care should be provided within drug services, EDs, primary care, sexual health and mental health services in the UK. Expand
[Trends in Abuse of Biogenic Drugs in Parts of Germany 2007-2013].
The data from the PICs suggest abuse of biogenic drugs in parts of Germany is decreasing, probably caused by the competition with new synthetic designer drugs. Expand
[Psychoactive plant species--actual list of plants prohibited in Poland].
According to the Act on Counteracting Drug Addiction (20-th of March, 2009), the list of federally prohibited plants in Poland was expanded to include 16 new species, which are now prohibited in Poland, their biochemical ingredients and their influence on the human organism. Expand
Blood oxygen level–dependent functional magnetic resonance imaging and magnetoencephalography have been employed for in vivo brain imaging in humans after administration of a psychedelic, and results indicate that intravenously administered psilocybin and LSD produce decreases in oscillatory power in areas of the brain’s default mode network. Expand
Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples
The objective of this work is to review the toxicological aspects, traditional use/therapeutic potential and the analytical methods developed in biological matrices in twelve plant specimens. Expand


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The rate of serious emotional disturbance caused by peyote, a hallucinogenic plant containing mescaline in an American Indian religion is found to be very low, probably because the feelings evoked by the drug experience are channeled by church belief and practice into ego-strengthening directions and there are built-in safeguards against bad reactions. Expand
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To the Editor: Botulism causes skeletal-muscle weakness resulting from bacterial exotoxins that irreversibly block the release of acetylcholine from presynaptic motor neurons. We report three cases...
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