Petchienes A-E, Meroterpenoids from Ganoderma petchii.


Petchienes A-E (1-5), five new meroterpenoids, were isolated from the fruiting bodies of Ganoderma petchii. Their structures, including absolute configurations, were elucidated by means of spectroscopic and computational methods. Compound 4 was isolated as a racemic mixture, which was finally purified by chiral HPLC to yield individual (-) and (+)-antipodes. Biological evaluation showed that compounds 2 and (-)-4 could increase intracellular free calcium concentration at 10 μM in HEK-293 cells.

Cite this paper

@article{Gao2015PetchienesAM, title={Petchienes A-E, Meroterpenoids from Ganoderma petchii.}, author={Qin-Lei Gao and Ping-Xia Guo and Qi Luo and Hui Yan and Yong-Xian Cheng}, journal={Natural product communications}, year={2015}, volume={10 12}, pages={2019-22} }