Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study.

@article{Landgren2009PesticideEA,
  title={Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study.},
  author={Ola Landgren and Robert A Kyle and Jane A. Hoppin and Laura E. Beane Freeman and James R. Cerhan and Jerry A. Katzmann and S Vincent Rajkumar and Michael C. R. Alavanja},
  journal={Blood},
  year={2009},
  volume={113 25},
  pages={6386-91}
}
Pesticides are associated with excess risk of multiple myeloma, albeit inconclusively. We included 678 men (30-94 years) from a well-characterized prospective cohort of restricted-use pesticide applicators to assess the risk of monoclonal gammopathy of undetermined significance (MGUS). Serum samples from all subjects were analyzed by electrophoresis performed on agarose gel; samples with a discrete or localized band were subjected to immunofixation. Age-adjusted prevalence estimates of MGUS… CONTINUE READING