Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp.

@article{Davis2010PestalactamsAN,
  title={Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp.},
  author={Rohan A Davis and Anthony R Carroll and Katherine Thea Andrews and Glen M Boyle and Truc Linh Tran and Peter C Healy and John Alexander Kalaitzis and Roger Graham Shivas},
  journal={Organic & biomolecular chemistry},
  year={2010},
  volume={8 8},
  pages={
          1785-90
        }
}
Chemical investigations of a fermentation culture from the endophytic fungus Pestalotiopsis sp. yielded three novel caprolactams, pestalactams A-C (). The structures of were determined by analysis of 1D and 2D-NMR, UV, IR, and MS data. The structure of pestalactam A was confirmed following single crystal X-ray diffraction analysis. Pestalactams A-C are the first C-7 alkylated caprolactam natural products to be reported. Pestalactams A () and B () were tested against two different strains of the… CONTINUE READING

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