Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness?

@article{Sporn2004PervasiveDD,
  title={Pervasive developmental disorder and childhood-onset schizophrenia: comorbid disorder or a phenotypic variant of a very early onset illness?},
  author={A. Sporn and A. Addington and N. Gogtay and Anna E. Ord{\'o}{\~n}ez and J. Rapoport},
  journal={Biological Psychiatry},
  year={2004},
  volume={55},
  pages={989-994}
}
  • A. Sporn, A. Addington, +2 authors J. Rapoport
  • Published 2004
  • Medicine, Psychology
  • Biological Psychiatry
  • BACKGROUND Childhood-onset schizophrenia (COS) is a severe form of the adult-onset disorder with a high rate of premorbid developmental abnormalities. Early symptoms of pervasive developmental disorder (PDD) have been reported in five independent studies of COS. In this study, we compared evidence for premorbid PDD as a nonspecific manifestation of impaired neurodevelopment seen in schizophrenia, or as an independent risk factor for COS. METHODS Diagnosis of past or current autism or PDD was… CONTINUE READING
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    References

    SHOWING 1-10 OF 44 REFERENCES
    Childhood-onset schizophrenia: rare but worth studying
    • 202
    Symptom development in childhood onset schizophrenia.
    • 196
    Childhood-onset schizophrenia: editors' introduction.
    • 44
    • PDF
    Looking for childhood-onset schizophrenia: the first 71 cases screened.
    • 209
    The clinical presentation of childhood-onset schizophrenia.
    • 120
    • PDF
    Child and adolescent (juvenile onset) schizophrenia. A case control study of premorbid developmental impairments.
    • C. Hollis
    • Psychology, Medicine
    • The British journal of psychiatry : the journal of mental science
    • 1995
    • 192
    Children with schizophrenia spectrum and depressive disorders: a comparative study of premorbid adjustment, onset pattern and severity of impairment.
    • J. Asarnow, S. Ben-Meir
    • Psychology, Medicine
    • Journal of child psychology and psychiatry, and allied disciplines
    • 1988
    • 125
    Childhood schizophrenia: present but not accounted for.
    • 96
    Schizophrenia with childhood onset: a phenomenological study of 38 cases.
    • 157