Pertussis Vaccine Effectiveness in the Setting of Pertactin-Deficient Pertussis.

@article{Breakwell2016PertussisVE,
  title={Pertussis Vaccine Effectiveness in the Setting of Pertactin-Deficient Pertussis.},
  author={Lucy Breakwell and Patsy Tassler Kelso and Christine Finley and Susan Schoenfeld and Brant Goode and Lara K. Misegades and Stacey W. Martin and Anna M. Acosta},
  journal={Pediatrics},
  year={2016},
  volume={137 5}
}
BACKGROUND In the United States, the proportion of Bordetella pertussis isolates lacking pertactin, a component of acellular pertussis vaccines, increased from 14% in 2010 to 85% in 2012. The impact on vaccine effectiveness (VE) is unknown. METHODS We conducted 2 matched case-control evaluations in Vermont to assess VE of the 5-dose diphtheria, tetanus, and acellular pertussis vaccine (DTaP) series among 4- to 10-year-olds, and tetanus, diphtheria, and acellular pertussis vaccine (Tdap) among… CONTINUE READING