Perthes' disease: deprivation and decline

@article{Perry2011PerthesDD,
  title={Perthes' disease: deprivation and decline},
  author={Daniel C. Perry and Colin E. Bruce and Daniel Pope and Peter H. Dangerfield and Mary Jane Platt and Andrew J Hall},
  journal={Archives of Disease in Childhood},
  year={2011},
  volume={96},
  pages={1124 - 1128}
}
Introduction Perthes' disease is a childhood hip disorder which frequently precipitates premature osteoarthritis necessitating joint replacement in young adults. The highest incidence reported worldwide is in Merseyside, UK, where a unique disease register is maintained. Objective To describe the temporal trends in disease incidence in a geographically defined area of Merseyside, and to examine the relationship to area deprivation. Design Descriptive observational study utilising a regional… Expand
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A propensity to associated congenital anomalies suggests an intrauterine cause, and the lack of concordance in twins suggests a strong environmental etiology, with little evidence to suggest a genetic predisposition. Expand
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TLDR
The demographic data of a group of 240 children who presented with Perthes' disease in Greater Glasgow, where the mean deprivation scores are substantially greater than in the rest of Scotland, were examined to see if this association applied and whether other clues to the aetiology of Perthers' disease could be found. Expand
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TLDR
It is suggested that environmental influences may come into play some years before a child presents with pain in the hip, and there may be a genetic predisposition to the disease. Expand
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  • Medicine
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TLDR
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Perthes' disease of the hip in Liverpool
TLDR
Dr Thomas concludes: "there is no dramatic treatment for stroke," and, although he mentions various drugs that have been used, there is no evidence as to which patients will benefit from which treatment. Expand
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TLDR
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TLDR
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TLDR
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