Perthes’ disease of the hip: socioeconomic inequalities and the urban environment

@article{Perry2012PerthesDO,
  title={Perthes’ disease of the hip: socioeconomic inequalities and the urban environment},
  author={Daniel C. Perry and Colin E. Bruce and Daniel Pope and Peter H. Dangerfield and Mary Jane Platt and Andrew J Hall},
  journal={Archives of Disease in Childhood},
  year={2012},
  volume={97},
  pages={1053 - 1057}
}
Introduction Perthes’ disease is a puzzling childhood hip disorder for which the aetiology is unknown. It is known to be associated with socioeconomic deprivation. Urban environments have also been implicated as a risk factor, however socioeconomic deprivation often occurs within urban environments and it is unclear if this association is the result of confounding. The objective of the current work was to gain a greater understanding of the influence of the urban/rural environment in Perthes… Expand
Incidence of Perthes’ disease in children born between 1973 and 1993
TLDR
There is a association between the incidence of Perthes’ disease and the socioeconomic status of the parents, and this study confirms that there is an association between these factors and the incidence was lower when the fathers were in the highest income bracket. Expand
Unravelling the enigma of Perthes disease.
  • D. Perry
  • Medicine
  • Annals of the Royal College of Surgeons of England
  • 2013
TLDR
Despite a falling incidence, Perthes disease remains an important cause of child morbidity and exemplifies socioeconomic inequalities and a deprivation-related exposure, acting early in development, appears critical. Expand
A case control study to determine the association between Perthes' disease and the recalled use of tobacco during pregnancy, and biological markers of current tobacco smoke exposure
TLDR
An association exists between tobacco smoke exposure and Perthes' disease but the authors remain unable to disentangle the association with socioeconomic deprivation. Expand
What are the Demographics and Epidemiology of Legg-Calvé-Perthes Disease in a Large Southern California Integrated Health System?
TLDR
The authors' study of a large integrated healthcare system in Southern California revealed an increased association of male sex and young age (2 to 5 years old) with LCPD and the overall incidence was lower overall than previously reported, although the incidence seen in white patients was similar to that in prior studies. Expand
The epidemiology and etiology of Perthes disease.
TLDR
A propensity to associated congenital anomalies suggests an intrauterine cause, and the lack of concordance in twins suggests a strong environmental etiology, with little evidence to suggest a genetic predisposition. Expand
Aetiology of Legg-Calvé-Perthes disease: A systematic review
TLDR
The literature available on the aetiology of LCPD presents major limitations in terms of great heterogeneity and a lack of high-profile studies, so more studies are needed to understand the complex and multifactorial genesis of the avascular necrosis characterizing the disease. Expand
Is Legg-Calvé-Perthes Disease a Local Manifestation of a Systemic Condition?
TLDR
The hypothesis that Legg-Calvé-Perthes disease is the local manifestation of a systemic disease, indicative of an underlying common disease pathway that requires further investigation is strengthened. Expand
Influence of passive smoking on the onset of Legg-Calvè-Perthes disease: a systematic review and meta-analysis
The relationship between passive smoking and the onset of Legg-Calvè-Perthes disease is still controversial. Therefore, we conducted the study to systematically evaluate and analyze the relationship.Expand
Legg-Calvé-Perthes disease and the risk of ADHD, depression, and mortality
TLDR
Individuals with LCPD have a higher mortality risk, with higher risk of suicide and cardiovascular diseases, and hyperactivity could expose the femoral head to higher mechanical stress and contribute to the etiology of LCPD. Expand
Equality in Hip Arthroscopy Outcomes Can Be Achieved Regardless of Patient Socioeconomic Status
TLDR
Regardless of SES, patients were able to achieve significant improvements in several PROMs after hip arthroscopy for FAIS and labral tear at the minimum 2-year follow-up, and patients from all SES groups achieved clinically meaningful improvement at similar rates. Expand
...
1
2
...

References

SHOWING 1-10 OF 24 REFERENCES
Perthes' disease: deprivation and decline
TLDR
The magnitude of the association with deprivation, and the changing incidence, strongly suggest that environmental factor(s) are a major aetiological determinant in Perthes' disease. Expand
Epidemiology of Perthes' disease.
TLDR
The normal birthweight and absence of association with known prenatal influences suggest a determinant acting in early postnatal life, which points to major environmental influences in the etiology associated with poverty. Expand
Deprivation, urbanisation and Perthes' disease in Northern Ireland.
TLDR
While the incidence of Perthes' disease was found to be associated with indicators of the level of deprivation for areas, there was no evidence to suggest that there was an increased risk in urban areas; the highest rate was found in the most deprived rural category. Expand
Racial and geographic factors in the incidence of Legg-Calvé-Perthes' disease: a systematic review.
TLDR
Latitude was a strong predictor of disease, even after adjustment for race, and latitude demonstrates a strong association with incidence, which may offer new epidemiologic insights into the determinants of Perthes' disease. Expand
Legg-Calvé-Perthes disease in the UK: geographic and temporal trends in incidence reflecting differences in degree of deprivation in childhood.
TLDR
The declining incidence, along with the geographic variation, suggests that a major etiologic determinant in Legg-Calvé-Perthes disease is environmental and closely linked to childhood deprivation. Expand
The incidence of Perthes' disease in Southwest Scotland.
TLDR
A higher incidence of Perthes' disease was noted in areas with a lower population density compared with those with a higher density, and no correlation between population density and deprivation scores for individual electoral wards within the region. Expand
The epidemiology and aetiology of Perthes' disease in Norway. A nationwide study of 425 patients.
TLDR
The findings point toward a single cause, either genetic or environmental, acting prenatally in the aetiology of Perthes' disease, which was undertaken over a five-year period from January 1996. Expand
Perthes' disease of the hip in Liverpool.
TLDR
Analysis of all new cases that occurred in Liverpool and adjacent parts of Knowsley and Sefton during 1976-81 showed a steep gradient with social class, which supports the hypothesis that undernutrition is a causative factor in the disease. Expand
The incidence and distribution of Legg–Calvé–Perthes' disease in Liverpool, 1982–95
TLDR
It is suggested that environmental influences may come into play some years before a child presents with pain in the hip, and there may be a genetic predisposition to the disease. Expand
Environmental Tobacco and Wood Smoke Increase the Risk of Legg-Calvé-Perthes Disease
TLDR
This study provides further evidence that environmental tobacco smoke is associated with an increased risk of Legg-Calvé-Perthes disease and exposure to wood smoke also appears to be a risk factor. Expand
...
1
2
3
...