Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells.

@article{Leininger1991PertactinAA,
  title={Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells.},
  author={Elizabeth Leininger and Melanie Roberts and J G Kenimer and I. G. Charles and Neil T. Fairweather and Pavel Novotny and Michael W. Brennan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 2},
  pages={345-9}
}
A 69-kDa protein has been identified on the surface of the Gram-negative pathogen Bordetella pertussis that can elicit a protective immune response in animal models. This protein is associated with virulent strains of B. pertussis but its function has remained unclear. In this report we demonstrate that purified preparations of the 69-kDa outer membrane protein can promote the attachment of Chinese hamster ovary (CHO) cells. The interaction between the mammalian cells and this protein can be… CONTINUE READING
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