Perspectives on the rapid eye movement sleep switch in rapid eye movement sleep behavior disorder.

@article{Ramaligam2013PerspectivesOT,
  title={Perspectives on the rapid eye movement sleep switch in rapid eye movement sleep behavior disorder.},
  author={Vetrivelan Ramaligam and Michael C. Chen and Clifford B. Saper and Jun Lu},
  journal={Sleep medicine},
  year={2013},
  volume={14 8},
  pages={707-13}
}
Rapid eye movement (REM) sleep in mammals is associated with wakelike cortical and hippocampal activation and concurrent postural muscle atonia. Research during the past 5 decades has revealed the details of the neural circuitry regulating REM sleep and muscle atonia during this state. REM-active glutamatergic neurons in the sublaterodorsal nucleus (SLD) of the dorsal pons are critical for generation for REM sleep atonia. Descending projections from SLD glutamatergic neurons activate inhibitory… CONTINUE READING

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