Perspectives on brain tumor formation involving macrophages, glia, and neural stem cells.

@article{Seyfried2001PerspectivesOB,
  title={Perspectives on brain tumor formation involving macrophages, glia, and neural stem cells.},
  author={Thomas N. Seyfried},
  journal={Perspectives in biology and medicine},
  year={2001},
  volume={44 2},
  pages={263-82}
}
The incidence of brain tumors is rising in children and the elderly, but little is known about the mechanisms underlying brain tumor initiation and progression. In the 1940s, Zimmerman and coworkers exploited the tumor-promoting potential of polycyclic hydrocarbons to produce brain tumor models in adult mice that simulated the neuropathology of human brain… CONTINUE READING