Perspectives of zebrafish models of epilepsy: what, how and where next?

  title={Perspectives of zebrafish models of epilepsy: what, how and where next?},
  author={Adam Stewart and Daniel H Desmond and Evan J Kyzar and Siddharth Gaikwad and Andrew Dean Roth and Russell A Riehl and Christopher Collins and Louis Monnig and Jeremy Green and Allan Kalueff},
  journal={Brain research bulletin},
  volume={87 2-3},
Epilepsy is a complex brain disorder with multiple underlying causes and poorly understood pathogenetic mechanisms. Animal models have been indispensable tools in experimental epilepsy research. Zebrafish (Danio rerio) are rapidly emerging as a promising model organism to study various brain disorders. Seizure-like behavioral and neurophysiological responses can be evoked in larval and adult zebrafish by various pharmacological and genetic manipulations, collectively emphasizing the growing… CONTINUE READING

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