• Corpus ID: 85878511

Perspectives in Renin-Angiotensin-Aldosterone System Blockade: What's New?

@inproceedings{Balakumar2011PerspectivesIR,
  title={Perspectives in Renin-Angiotensin-Aldosterone System Blockade: What's New?},
  author={Pitchai Balakumar and Nidhi Sharma and Sonam Kathuria and Lalita Babbar and Nanjaian Mahadevan},
  year={2011}
}
The renin-angiotensin-aldosterone system (RAAS) plays a key role in the regulation of cardiovascular-renal function. However, its overactivation results in cardiovascular and renal abnormalities. Thus, drugs depressing the overactivity of RAAS are of potential therapeutic value in the management of cardiovascular and renal complications. The RAAS overactivation could be effectively inhibited by various agents at its different stages by means of inhibiting angiotensin-II (Ang-II) formation from… 
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