Perspectives Animal Models of Retinal Injury

  title={Perspectives Animal Models of Retinal Injury},
  author={Richard J. Blanch and Zubair Ahmed and Martin Berry and Robert H. Scott and Ann Logan},
Retinal injury is a common cause of profound and intractable loss of vision. Clinical outcomes are poor in both open and closed globe injuries because cell death, scarring, and a failure of tissue and axon regeneration are not ameliorated by current treatments. Much animal research is directed at understanding and modifying these pathologies, although results have yet to translate into clinical practice. Axotomy-induced retinal ganglion cell (RGC) death in mammals can be effectively reduced and… CONTINUE READING