Perspectives Am“B”valent: anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis


Accumulating evidence has designated B cells as central players in the pathogenesis of immune diseases. In the late 1990s, anti-CD20 monoclonal antibodies were developed for the treatment of B-cell nonHodgkin lymphomas, offering the opportunity to efficiently deplete the B-cell compartment for therapeutic immunointerventions. Several studies have since… (More)


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