Perspective: revisiting the field dependence of TROSY sensitivity.

  title={Perspective: revisiting the field dependence of TROSY sensitivity.},
  author={Koh Takeuchi and Haribabu Arthanari and Gerhard Wagner},
  journal={Journal of biomolecular NMR},
  volume={66 4},
The discovery of the TROSY effect (Pervushin et al. in Proc Natl Acad Sci USA 94:12366-12371, 1997) for reducing transverse relaxation and line sharpening through selecting pathways in which dipole-dipole and CSA Hamiltonians partially cancel each other had a tremendous impact on solution NMR studies of macromolecules. Together with the methyl TROSY… CONTINUE READING