Personalized Drug Analysis in B Cell Chronic Lymphocytic Leukemia Patients

@inproceedings{Liu2017PersonalizedDA,
  title={Personalized Drug Analysis in B Cell Chronic Lymphocytic Leukemia Patients},
  author={Guozhen Liu and Xiaoling Hu and Lei Gao and Zhenjun Feng},
  booktitle={Medical science monitor : international medical journal of experimental and clinical research},
  year={2017}
}
BACKGROUND B cell chronic lymphocytic leukemia (B-CLL) is the most common adult leukemia in the Western world. Although therapeutic advances have notably improved the outcome for many patients, B-CLL remains an incurable disease. The purpose of this study was to search for therapeutic drugs based on altered pathways in individual patients. MATERIAL AND METHODS Genes from microarray data were mapped to 300 Homo sapiens-related pathways. Individual pathway aberrance analysis was used to identify… CONTINUE READING