• DOI:10.1016/j.reprotox.2017.08.010
Corpus ID: 40461953

Persistent testicular structural and functional alterations after exposure of adult rats to atrazine.

@article{MartinsSantos2017PersistentTS,
  title={Persistent testicular structural and functional alterations after exposure of adult rats to atrazine.},
  author={Elis{\^a}ngela Martins-Santos and C. Pimenta and P. Campos and Mariana Brand{\~a}o Franco and D. Gomes and G. B. Mahecha and C. A. Oliveira},
  journal={Reproductive toxicology},
  year={2017},
  volume={73},
  pages={
          201-213
        }
}

• Elisângela Martins-Santos, C. Pimenta, +4 authors C. A. Oliveira
• Published 2017
• Biology, Medicine
• Reproductive toxicology

Atrazine is an endocrine disruptor affecting testicular steroidogenesis, and promoting testicular atrophy and 3β-HSD reduction. However, it remains unknown whether these effects are reversible or permanent. To address this issue was the aim of this study. Exposition of rats to 200mg/kg of atrazine resulted in transient increase in testicular weight, seminiferous tubules dilation and atrophy, and reduction in Leydig cell 3β-HSD. Testicular atrophy and 3β-HSD reduction were more pronounced after… Expand

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