Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and invasiveness.

@article{Klingenberg2007PersistentSO,
  title={Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and invasiveness.},
  author={Claus Klingenberg and Arild Erlend R\onnestad and Annaliesa S. Anderson and Tore Gunnar Abrahamsen and Julie Zorman and Amer E. Villaruz and Trond Flaegstad and Michael Otto and Johanna Ulrica Ericson Sollid},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2007},
  volume={13 11},
  pages={1100-11}
}
Coagulase-negative staphylococci (CoNS) are the major cause of nosocomial bacteraemia in neonates. The aim of this study was to investigate whether persistent strains of CoNS possess specific bacterial characteristics as compared with sporadic non-cluster isolates. In total, 180 blood culture isolates (95 contaminants and 85 invasive isolates) obtained from a single neonatal unit over a 12-year period were studied. Pulsed-field gel electrophoresis (PFGE) identified 87 persistent CoNS strains… CONTINUE READING

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