Persistent storage capability impairs decision making in a biophysical network model

@article{Standage2011PersistentSC,
  title={Persistent storage capability impairs decision making in a biophysical network model},
  author={Dominic I. Standage and Martin Par{\'e}},
  journal={Neural networks : the official journal of the International Neural Network Society},
  year={2011},
  volume={24 10},
  pages={1062-73}
}
Two long-standing questions in neuroscience concern the mechanisms underlying our abilities to make decisions and to store goal-relevant information in memory for seconds at a time. Recent experimental and theoretical advances suggest that NMDA receptors at intrinsic cortical synapses play an important role in both these functions. The long NMDA time constant is suggested to support persistent mnemonic activity by maintaining excitatory drive after the removal of a stimulus and to enable the… CONTINUE READING
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