Persistent seizures following left temporal lobe surgery are associated with posterior and bilateral structural and functional brain abnormalities.

@article{Keller2007PersistentSF,
  title={Persistent seizures following left temporal lobe surgery are associated with posterior and bilateral structural and functional brain abnormalities.},
  author={Simon S. Keller and Paul Cresswell and Christine Denby and Udo C. Wieshmann and Paul Eldridge and Gus Baker and Neil Roberts},
  journal={Epilepsy research},
  year={2007},
  volume={74 2-3},
  pages={131-9}
}
PURPOSE To perform a quantitative MRI and retrospective electrophysiological study to investigate whether persistent post-surgical seizures may be due to brain structural and functional abnormalities in temporal lobe cortex beyond the margins of resection and/or bilateral abnormalities in patients with temporal lobe epilepsy (TLE). METHODS In 22 patients with left TLE and histopathological evidence of hippocampal sclerosis, we compared pre-surgical brain morphology between patients surgically… CONTINUE READING

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