Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique.

@article{Madsen1995PersistentRO,
  title={Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique.},
  author={Per Lav Madsen and Steen G. Hasselbalch and Luise Hagemann and Karsten Skovgaard Olsen and Jens B{\"u}low and S\oren Holm and Gordon Wildschi\odtz and Olaf Bjarne Paulson and Niels A. Lassen},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1995},
  volume={15 3},
  pages={485-91}
}
Global cerebral blood flow (CBF), global cerebral metabolic rates for oxygen (CMRO2), and for glucose (CMRglc), and lactate efflux were measured during rest and during cerebral activation induced by the Wisconsin card sorting test. Measurements were performed in healthy volunteers using the Kety-Schmidt technique. Global CMRO2 was unchanged during cerebral activation, whereas global CBF and global CMRglc both increased by 12%, reducing the molar ratio of oxygen to glucose consumption from 6.0… CONTINUE READING
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